Multimodal Analgesia for the Reduction of Postoperative Opioid Consumption
- Conditions
- Pain
- Interventions
- Drug: Multimodal analgesia
- Registration Number
- NCT03817034
- Lead Sponsor
- Massachusetts General Hospital
- Brief Summary
The investigators are performing this research study to investigate the efficacy of local infiltration of the surgical wound combining dexmedetomidine, ropivacaine, and ketorolac (treatment group) versus the current standard of care (historical control group), for post-operative pain management.
- Detailed Description
During this research study, patients recommended for a rectus sheath block during surgery will receive a novel combination of non-opioid drugs. Data from the treatment group will be compared to surgical outcomes of a historically matched control group to investigate the ability of this drug combination to reduce post-operative pain and post-operative opioid consumption.
Recruitment & Eligibility
- Status
- WITHDRAWN
- Sex
- All
- Target Recruitment
- Not specified
- Age greater than 18 years
- American Society of Anesthesiologist Physical Status Classification 1-3
- Undergoing surgery requiring a rectus sheath block
- American Society of Anesthesiologist Physical Status Classification of 4 or beyond
- history of opiate of illicit substance abuse, chronic pain, or neurological dysfunction
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description Multimodal Analgesia Multimodal analgesia -
- Primary Outcome Measures
Name Time Method Change in post-operative opioid consumption 48 hours Decreased post-operative opioid consumption associated with use of multimodal analgesia
Change in post-operative pain scores 48 hours Decreased post-operative pain scores associated with use of multimodal analgesia
- Secondary Outcome Measures
Name Time Method