Effect of trutyadi churna in amavata with special reference to rheumatoid arthritis.

Recruiting

• Conditions: Autoinflammatory syndrome, unspecified. Ayurveda Condition: AMAVATAH,

• Registration Number: CTRI/2021/08/035463
• Lead Sponsor: DR VISHNUPRIYA SEETHARAM

Brief Summary

A Current study will be in single arm clinical study to evaluate the effect of trutyadi churna in amavata with special reference to rheumatoid arthritis. in this study, minimum 20 patients diagnosed with amavata will be chosen. The trutyadi churna will be given as 500mg capsules (8 capsules TID) after food. Anupana will be sita sadhita jala. The drug is given for 14 days followed by a follow up period of 14 days.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2021-05-08
• Study Start: 2021-10-08

Recruitment & Eligibility

• Status: Open to Recruitment
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

• ACR 2010 CRITERIA FOR RHEUMATOID ARTHERITIS.
• BOTH SERO POSITIVE AND SERO NEGATIVE CASES OF RA FACTOR.
• PATIENTS OF AMAVATA SUFFERING FROM 1 TO 10 YEARS OF DURATION.

Exclusion Criteria

• PATIENTS OF AGE GROUP LESS THAN 18 AND MORE THAN 70.
• PREGNANT AND LACTATING MOTHERS OR THOSE ATTEMPTING TO CONCEIVE.
• PATIENTS OF SEVERE STRUCTURAL DEFORMITIES WILL BE EXCLUDED FROM THE STUDY.
• PATIENTS OF RA WITH ANY SYSTEMIC ILLNESS (HEPATIC FAILURE, RENAL FAILURE, ISCHEMIC HEART DISEASE, MALIGNANCY ETC).
• PATIENTS SUFFERING FROM CONNECTIVE TISSUE DISORDERS OTHER THAN RA.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
SWOLLEN JOINT COUNT OVER TIME [TIME FRAME: BASELINE AND DAY 14]	BASELINE AND DAY 14]
TENDER JOINT COUNT OVER TIME [BASELINE AND DAY 14]	BASELINE AND DAY 14]
CHANGE IN AVERAGE RANGE OF MOVEMENTS OF AFFECTED JOINTS OVER TIME [TIME FRAME : BASELINE AND DAY 14]	BASELINE AND DAY 14]
ASSESMENT OF PAIN [TIME FRAME:BASELINE AND DAY 14] BY VISUAL ANALOG SCALE	BASELINE AND DAY 14]
STIFFNESS OF JOINTS ASSESSED OVER TIME WITH LIKERT SCALE[ TIME FRAME:BASELINE AND DAY 14]	BASELINE AND DAY 14]
CHANGE FROM BASELINE IN DISEASE ACTIVITY SCORE 28 [TIME FRAME : BASELINE AND DAY 14]	BASELINE AND DAY 14]

Secondary Outcome Measures

Name	Time	Method
ERYTHROCYTE SEDIMENTATION RATE OVER TIME [TIME FRAME: BASELINE AND DAY 14]	HB%

Trial Locations

Locations (1)

Shri Dharamasthala Manjunatheshwara college of ayurveda kuthpady,udupi; 🇮🇳 Udupi, KARNATAKA, India

Shri Dharamasthala Manjunatheshwara college of ayurveda kuthpady,udupi

🇮🇳Udupi, KARNATAKA, India

DR VISHNUPRIYA SEETHARAM

Principal investigator

9400848984

vishnupriyaseetharam@gmail.com