Quantifying blood flow in the aorta using phase-contrast 4D flow MRI

Completed

• Conditions: Blood flow dynamics in healthy aorta; Aorta blood flow; aorta and side branches' anatomy

• Registration Number: NL-OMON51196
• Lead Sponsor: niversity of Twente

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2022-10-27
• Last Update Posted: 15 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 20

Inclusion Criteria

Healthy men or women, being older than 18 years.;
BMI <= 30.;
Willingness to undergo MRI scans.;
Signed informed consent (IC).

Exclusion Criteria

Arithmetic heartbeat.;
Any history of cardiovascular disease
The standard MRI exclusion criteria (such as pacemakers, cerebral vascular
clips, pregnancy, claustrophobia).

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>To obtain blood flow boundary conditions from ascending aorta to internal and<br /><br>external iliac arteries, including branched arteries such as subclavian<br /><br>arteries, common carotid artery and visceral branch vessels. The main goal is<br /><br>to acquire *volumetric flow rate*, *4D velocity fields (i.e., 3D spatial<br /><br>coordinates and temporal points over the cardiac cycle)*, and *3D geometry of<br /><br>the entire aorta and its side branches* in the aortic arch and abdomen FOVs.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Combining the obtained MRI data from aortic arch and abdomen regions, and<br /><br>reconstruct a general aortic segmentation.</p><br>