IRCT2017083027520N9
Recruiting
Phase 1
A Clinical trial to assess the effect of Natural Killer Cell transplantation in treatment of patients with Acute lymphoblastic leukemia (ALL) and chronic lymphocytic leukemia (CLL)
Stem Cell And Regenerative Medicine Institute0 sites10 target enrollmentTBD
Overview
- Phase
- Phase 1
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- Stem Cell And Regenerative Medicine Institute
- Enrollment
- 10
- Status
- Recruiting
- Last Updated
- 8 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\-Age range of 18\- 25 years for ALL patients; 2\-Age range over 50 years for patients with CLL; 3\- Those who have a proper cell donors with incongruent KIR (Haploidentical KIR\-L mismatched donor); 4\- Patients with adequate organ function; 5\-Access to the patient for the continuation of treatment and follow\-up (preferably from Azeri\-speaking patients for easier access and removal of the Zentique variable);
- •Exclusion criteria : 1\-Patients with active and uncontrolled infections; 2\-Abnormal kidney, lung and liver function, measured by serum creatinine (serum creatinine\> 2 mg / dl), saturated oxygen O2 \= 96%) (Sat and liver enzymes (ALT / AST\> 2\.5 x N); 3\-Patients with Down syndrome; 4\- Patients with acute promyelocytic leukemia
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
Not specified
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