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: The effect of curcumin supplementation as adjunctive therapy in the treatment of patients with bipolardisorder-Depressio

Phase 3
Recruiting
Conditions
Bipolar disorder.
Bipolar disorder
Registration Number
IRCT20231206060281N1
Lead Sponsor
Gorgan University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
72
Inclusion Criteria

Consent of the patient or the patient's guardian to participate in the study
Diagnosing a patient's bipolar depression disorder by a psychiatrist based on V-DSM criteria
Age over 18 years

Exclusion Criteria

Other psychiatric disorders
Chronic inflammatory diseases
Taking herbal medicines
History of allergy to herbal medicines and turmeric
Pregnancy or breastfeeding
Patients taking anticoagulant and antiplatelet drugs such as aspirin, clopidogrel, heparin, enoxaparin, warfarin

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
The effectiveness of the treatment is the main outcome of this study that will be measured with the questionnaire. The questionnaire will be completed for patients before and after the intervention. The difference in the questionnaire score will be considered the treatment effect. Timepoint: The beginning and end of the study. Method of measurement: the Persian Version of Bipolar Depression Rating Scale.
Secondary Outcome Measures
NameTimeMethod
Measurement of drug side effects. Timepoint: End of week 6 and 12. In order for the doctor to ensure that the conditions of all patients are the same and to control the effects of treatment with standard drugs, all patients will receive the usual standard treatment for 6 weeks. Then, before dividing the patients into two groups and starting the intervention, the questionnaire will be completed by the assistant psychiatrist. Then the patients will be randomly divided into two groups and will receive the assigned treatment for 6 weeks. The questionnaire will be completed again for them. Method of measurement: Standard questionnaire.
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