Multimodality medical imaging analysis for bone/frailty-brain crosstalk
Not Applicable
Recruiting
- Conditions
- Osteoporosis
- Registration Number
- JPRN-UMIN000035762
- Lead Sponsor
- Institute of Development, Aging and Cancer, Tohoku University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 500
Inclusion Criteria
Not provided
Exclusion Criteria
1) Patients who have already been participated in other research studies. 2) Patients who has a medical history of musculoskeletal, parathyroid, psychological disorders and brain tumors. 3) Contraindication to undergoing MRI scan.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Mini-mental state examination (MMSE) scores.
- Secondary Outcome Measures
Name Time Method Hand grip, muscle mass, gait parameters (walking speed, cadence, acceleration), blood exam, Areas related to cognitive impairment on brain MRI and SPECT-rCBF. Blood and/or cerebrospinal fluid specimens are stocked for further genomic analysis only after the patients' approval.