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VITAMin Insufficiency in esophagogastric Neoplasms or the VITAMIN study

Conditions
Esophageal cancer and gastric cancer
Registration Number
NL-OMON25636
Lead Sponsor
GIKAVI
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
Not specified
Target Recruitment
248
Inclusion Criteria

A potential subject who meets any of the following criteria will be included for participation in this study:
- Patients =18 years of age who underwent an esophagectomy or (sub)total gastrectomy for malignancy with no signs of postoperative recurrence of disease.
- Written voluntary informed consent (IC).

Exclusion Criteria

A potential subject who meets any of the following criteria will be excluded from participation in this study:
- Patients that underwent a wedge resection of the stomach
- Malignant disease recurrence
- Metastases
- Patients that are not capable to take supplementation due to altered mental status or
swallow difficulties
- No signed informed consent
- Patients who are receiving chemotherapy
- Patients with high vitamin status at baseline

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
To identify which micronutrient deficiencies are most common after surgery for esophagogastric neoplasms and to observe the effect of supplementation.
Secondary Outcome Measures
NameTimeMethod
• The incidence of exocrine pancreatic insufficiency<br>• To prevent consequences of micronutrient deficiencies as iron-deficiency anemia,<br>rickets, folic acid anemia, disturbed vision, mental declination.<br>• To measure quality of life post-operative<br>• To measure quality of life regarding vitality post supplementation.
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