A Pragmatic Remote Approach to Improve Transitions of Care and Retention in Opioid Use Disorder Treatment
试验速览
- 阶段
- 1 期
- 状态
- 招募中
- 入组人数
- 20
- 试验地点
- 2
- 主要终点
- Feasibility (successful receipt)
研究概览
简要总结
This pilot study evaluates the feasibility, acceptability, and preliminary effectiveness of mailing buprenorphine to individuals with opioid use disorder (OUD) following medical hospitalization. The intervention aims to improve retention in treatment by overcoming barriers such as transportation and pharmacy access.
详细描述
This single-center, hybrid type 3 pilot study will enroll 20 medically hospitalized patients with OUD who are initiated on buprenorphine during their inpatient stay. Participants will be discharged with a supply of buprenorphine and enrolled in the MOUD Direct Delivery (MOUDDD) Program, which mails monthly refills directly to their homes. The study will evaluate the feasibility (successful delivery), acceptability (patient-reported measures), and preliminary effectiveness (treatment retention at 1, 3, and 6 months) of mailing buprenorphine. Secondary outcomes include quality of life, adherence, overdose, and healthcare utilization. The intervention leverages existing mail-order pharmacy protocols and aims to inform scalable strategies for improving transitions of care and retention in OUD treatment.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •English-speaking
- •Diagnosed with OUD and initiated on buprenorphine during hospitalization
- •Discharging to a South Carolina address with a stable mailbox
- •Access to phone or computer
排除标准
- •Active psychosis or suicidal ideation
- •Severe medical or neurocognitive impairment
- •Pending incarceration
研究组 & 干预措施
Mailed Medications
There is no comparison arm. This pilot study evaluates the feasibility of mailing medications to patients.
干预措施: strategy of mailing buprenorphine (Other)
结局指标
主要结局
Feasibility (successful receipt)
时间窗: From enrollment to the end of the study at 6 months
Successful delivery and receipt of medication defined by self-report and phone/text/video confirmation to receive code
Successful receipt
时间窗: From enrollment to the end of study at 6 months.
Feasibility is defined by the successful receipt of the buprenorphine prescriptions in the mail by the intended participants. Successful receipt defined by self-report and phone/text/video confirmation from participant. Delivery failure is defined as delay in receipt of medication by \>48 hours by the mail delivery service.
Retention in treatment
时间窗: time of study enrollment to end of study at 6 months
Preliminary effectiveness of mailing buprenorphine will be measured by retention in treatment. This is defined by the proportion of participants retained in buprenorphine treatment at 1,3, and 6 months after discharge.
次要结局
未报告次要终点
研究者
Allison Smith
Associate Professor-Faculty
Medical University of South Carolina