The Effect of Periarticular Injection on Postoperative Intravenous Morphine Consumption and Functional Recovery in Combination with Continuous Femoral Nerve Block and Spinal Anesthesia with Small Dose Intrathecal Morphine in Patients undergoing Total Knee Arthroplasty : A Randomized, Single-Blind, Controlled Clinical Trial
Not Applicable
Withdrawn
- Conditions
- unilateral total knee arthroplasty
- Registration Number
- TCTR20150714002
- Lead Sponsor
- Chaophraya Yommarat Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Withdrawn
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
-ASA physical status I-III
-Age 20-75 years old
-Body weight ≥45 kgs.
Exclusion Criteria
-unable to evaluate visual analogue scale (VAS) of pain
-unable to use patient-controlled analgesia (PCA) device
-contraindications to spinal anesthesia or CFNB (coagulopathy, progressive neurological deficit, intracranial space occupying lesion, unstable hemodynamic state, local infection at site of injection and patient refusal)
-allergy to any drugs used in this study
-inadequate level of spinal anesthesia or CFNB
- start case after 12.00 a.m.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 48 hours postoperative morphine consumption 48 hours after the operation record morphine consumption by using PCA device in milligram
- Secondary Outcome Measures
Name Time Method Postoperative morphine consumption during 0 - 4, 4 - 8, 8 - 24, 24 - 48 and 0 - 24 hours interval 0 - 4, 4 - 8, 8 - 24, 24 - 48 and 0 - 24 hours after the operation record morphine consumption by using PCA device in each time in milligram,Pain score at rest, 45 degree knee flexion, maximal knee flexion and sitting on the morning of POD1 on the morning of postoperative day 1 and postoperative day 2 record VAS in millimeter,Range of motion on the morning of POD1 and POD2 on the morning of postoperative day 1 and postoperative day 2 by using goniometer in degree,Side effects 48 hours after the operation using a questionnaire interview in yes or no