Optimizing Open Label Placebo Rationales
Not Applicable
Not yet recruiting
- Conditions
- Chronic Pain
- Interventions
- Other: Placebo
- Registration Number
- NCT05952960
- Lead Sponsor
- Rhode Island Hospital
- Brief Summary
A 3-arm randomized trial where all chronic pain patients will receive honest placebos, but the information about the placebos will differ between conditions. Outcomes are measured for 21 days and a qualitative survey will be conducted.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- NOT_YET_RECRUITING
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
- chronic pain
- 18 years old
- English speaking
- have a smartphone or computer with video access
- Taking prescription opioids for chronic pain
- the chronic pain is concentrated into the patient's lower back.
Exclusion Criteria
- suspect an allergy to any placebo ingredient
- problematic substance use
- cancer diagnosis causing pain
- anticipated change in opioid script during the study period.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Suspension of Disbelief Rationale Placebo Rationale based on suspending disbelief about the placebo Mindfulness Rationale Placebo Rationale based on mindfulness meditation TAU Rationale Placebo Rationale based on prior OLP studies (e.g. Kaptchuk et al., 2010)
- Primary Outcome Measures
Name Time Method Pain Reports 21 days Brief Pain Inventory: Pain intensity and pain interference
- Secondary Outcome Measures
Name Time Method Opioids 21 Days Quantity of prescription opioids taken