Managing knee pain with simple analgesia: the efficacy, cost and adherence implications
Completed
- Conditions
- Osteoarthritis of the kneeMusculoskeletal Diseases
- Registration Number
- ISRCTN87954265
- Lead Sponsor
- Medical Research Council (MRC) (UK)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 244
Inclusion Criteria
1. Male and female patients over 55 years
2. Clinical diagnosis osteoarthritis of the knee
3. Current joint pain score greater than 30 on a 10 mm visual analogue scale
Exclusion Criteria
1. Serious concomitant illness
2. Other pain-related conditions
3. Abnormal liver function tests
4. History of analgesic abuse or overdose
5. Severe OA awaiting joint replacement
6. Psychological disorders requiring treatment
7. Patients unable to follow instructions/complete questionnaires.
8. Use of over the counter medication containing paracetamol for duration of the study
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Treatment trial: pain in the affected joint measured by 100 mm visual analogue scale <br>Adherence trial: Proportion of patients who adhere to the regimen for continuous paracetamol
- Secondary Outcome Measures
Name Time Method ot provided at time of registration