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Clinical Characteristics for the Critical Ill Patients With Klebsiella Pneumoniae Infection

Completed
Conditions
Drug Resistance
Registration Number
NCT04404582
Lead Sponsor
Fujian Provincial Hospital
Brief Summary

The detection of Klebsiella pneumoniae virulence gene and antibiotics resistance gene takes a long time and high cost with equipment requirements. Distinguishing the Klebsiella pneumoniae by gene were late for clinical treatment. Therefore, the investigators aim to study the clinical characteristics of critically ill patients with Klebsiella pneumoniae infection which expressed different drug sensitivity test results.

Detailed Description

Clinical data of adult patients in integrated ICUs of 6 hospitals of Fujian Province China from January 2015 to July 2019 were collected, who had been examined for sputum, urine, blood, pleural effusion, ascites, cerebrospinal fluid and wound secretions and other body fluid samples. And the results showed that Klebsiella pneumoniae was positive, including demographic data, underlying disease status, drug sensitivity test, infection-related indicators, life support, prognostic indicators.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
546
Inclusion Criteria
  • Adult whose body fluid were sampled during ICU stay and Klebsiella pneumoniae was detected, followed by drug sensitivity test (including reporting the test results after the patient was transferred out of ICU or died).
Exclusion Criteria
  • Age were less than 18 years old;
  • Patients stayed in ICU was less than 48 hours.

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
prognostic indicators30 day

30-day survival rate

ICU staysabout a mouth

the length that patients stay in ICU

Secondary Outcome Measures
NameTimeMethod
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