跳至主要内容
临床试验/CTRI/2024/05/066941
CTRI/2024/05/066941尚未招募2 期

A prospective randomized comparative study to evaluate efficacy of intrathecal dexamethasone and dexmedetomidine added as adjuvant to bupivacaine in pregnant patient posted for elective LSCS.

Jawaharlal Nehru Medical College1 个研究点 分布在 1 个国家目标入组 50 人开始时间: 2024年5月16日最近更新:

试验速览

阶段
2 期
状态
尚未招募
入组人数
50
试验地点
1
主要终点
The duration of postoperative analgesia is longer with dexamethasone as an adjuvant with bupivacaine.

研究概览

简要总结

In our study, we are comparing the duration of postoperative analgesia between bupivacaine with dexmedetomidine and bupivacaine with dexamethasone in an elective caesarian section posted under spinal anaesthesia. Also, we are going to see intraoperative hemodynamics, sedation, and shivering. Our hypothesis says that bupivacaine with dexamethasone has better post operative analgesia than dexmedetetomidine.

研究设计

研究类型
Interventional
分配方式
Random Number Table
盲法
Open Label

入排标准

年龄范围
18.00 Year(s) 至 40.00 Year(s)(—)
性别
Female

入选标准

  • ASA Grades 1 & 2 BMI 20 TO 30 No history of bleeding tendency No previous uterine operation except cesarian section Living foetus.

排除标准

  • ASA 3 & 4 Patient having systemic disease Severe coronary insufficiency BMI > 30 The patient requires repeat intrathecal bupivacaine.

结局指标

主要结局

The duration of postoperative analgesia is longer with dexamethasone as an adjuvant with bupivacaine.

时间窗: The time duration will be noted for the first rescue analgesia.

次要结局

  • Intraoperative hemodynamics(Prevention of perioperative shivering)

研究者

申办方类型
Private medical college

研究点 (1)

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