The effects of mastication and sweetness on cephalic phase responses

Completed

• Conditions: Overweight; Overgewicht of Obesitas; Obesity

• Registration Number: NL-OMON43316
• Lead Sponsor: Wageningen Universiteit

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 23 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 22

Inclusion Criteria

* Male
* Between 18-35 years old at the day of inclusion
* Able to understand and speak Dutch or English fluently or without difficulty
* BMI 18.5-25 kg/m2
* Good general health and appetite (F1 questionnaire and judge by the subject)
* Eating three meals a day around the same time (self-report, see F1 questionnaire)

Exclusion Criteria

* Dental pathologies such as known caries, full dentures or planning to undergo dental treatment
during the study
* Difficulties with swallowing, chewing and or eating
* Suffering from an endocrine or eating disorder, gastrointestinal illness or illness of the thyroid
gland or diabetes.
* Having taste or smell disorders (self-report)
* Braces (not including a dental wire) or oral piercing
* Smoking
* Consuming on average more than 28 glasses of alcohol per week
* Facial hair not willing to shave (due to facial markers video)
* Use of medication that may influence study outcomes ( see, F1 questionnaire)
* Allergies or intolerance to any ingredient of the model food or ad libitum lunch.
* Not willing to eat the model foods or ad libitum lunch because of eating habits, (religious)
believes or vegetarianism.
* Followed an energy restricted diet during the last 2 months
* Gained or lost 5 kg of body weight over the last half year
* High restrained eater according to the Dutch Eating Behaviour Questionnaire (men: score>2.9).
* Signed up for participating in another research study (with the exception of the EetMeetWeet
study).
* Employee of Human Nutrition (WUR)
* Thesis student or intern at the chair group of Sensory Science and Eating Behaviour Human
Nutrition (WUR). ;Exclusion after information meeting:
* Low score (< -1) for liking on a nine point likert scale or score with more than 2 points difference between the four different types of gel;Exclusion after training:
* After repeatedly practising the participant is not able to have a recovery rate of 85% of the dry weight of the gel.
* Hb value is not between 8.1-11.0 mmol/L at training
* Veins not suitable for placement of the indwelling cannula (judged by the research nurse).

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The main parameters of interest are glucose levels, Insulin, PP, Ghrelin, FFA<br /><br>and Leptin hormonal responses.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>The secondary study parameter is intake in gram during an ad libitum lunch<br /><br>meal. </p><br>