Continuous positive airway pressure in severe Covid-19 pneumonia: a feasibility and physiological end-point study

Raad van Bestuur van het AMC (Amsterdam)0 个研究点目标入组 13 人开始时间: 待定最近更新: 2024年2月28日

适应症

试验速览

暂无简介。

•A subject must meet all of the following criteria:
•- age > 18 years
•- Positive for Covid-19 (CORADS 5, i.e. highly likely Covid-19 on the low-dose CT scan, or PCR positive nasopharyngeal swab for SARS Coronavirus 2).
•- Admitted to Amsterdam UMC, location AMC.
•- A transcutaneous O2 saturation (SpO2) of 90% or less at 5 l/min oxygen administration via nasal canula.
•- Provide informed consent.

•-Hypercapnia (defined as arterial PCO2 > 6.0 kPa or 45 mmHg)
•-A history of moderate to severe Chronic Obstructive Pulmonary Disease (COPD, GOLD severity III or IV), restrictive lung disease, or Obesity Hypoventilation Syndrome
•-Need for intubation or admission to the Intensive Care Unit as determined by the responsible physician
•-Palliative care
•-Reduced consciousness
•-Unability to wear the mask due to anatomical / physical restriction (e.g. facial operations; bearded)
•-Unable to provide informed consent.

发起方

Raad van Bestuur van het AMC (Amsterdam)