NL-OMON28307Not yet recruitingNot Applicable
Continuous positive airway pressure in severe Covid-19 pneumonia: a feasibility and physiological end-point study
Raad van Bestuur van het AMC (Amsterdam)0 sites13 target enrollmentStarted: TBDLast updated:
Conditions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Not yet recruiting
- Sponsor
- Enrollment
- 13
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional
Eligibility Criteria
Inclusion Criteria
- •A subject must meet all of the following criteria:
- •- age > 18 years
- •- Positive for Covid-19 (CORADS 5, i.e. highly likely Covid-19 on the low-dose CT scan, or PCR positive nasopharyngeal swab for SARS Coronavirus 2).
- •- Admitted to Amsterdam UMC, location AMC.
- •- A transcutaneous O2 saturation (SpO2) of 90% or less at 5 l/min oxygen administration via nasal canula.
- •- Provide informed consent.
Exclusion Criteria
- •-Hypercapnia (defined as arterial PCO2 > 6.0 kPa or 45 mmHg)
- •-A history of moderate to severe Chronic Obstructive Pulmonary Disease (COPD, GOLD severity III or IV), restrictive lung disease, or Obesity Hypoventilation Syndrome
- •-Need for intubation or admission to the Intensive Care Unit as determined by the responsible physician
- •-Palliative care
- •-Reduced consciousness
- •-Unability to wear the mask due to anatomical / physical restriction (e.g. facial operations; bearded)
- •-Unable to provide informed consent.
Investigators
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