Effect of pregabalin on hemodynamic on pai

Phase 4

• Conditions: Spinal anesthesia.; Unspecified adverse effect of drug or medicament

• Registration Number: IRCT2014121020272N1
• Lead Sponsor: Deputy for research Zahedan University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

The non-emergency patients ASA class 1; Age 20 to 70 years; candidates for orthopedic surgery tibia fracture; the prior written consent from patient; social class and level of consciousness that patient is able to cooperate ;
   Exclusion criteria were the beginning of the study:
hemodynamic status is affected with diseases or conditions such as heart disease, diabetes, renal ;The history of allergy to gabapentin or Pregabalin, drug use, regular use of alcohol or smoking more than 5 years, the diseases of the brain and nerves ; spinal anesthesia during surgery after more than ninety minutes ; patients who require drugs that affect hemodynamic ; pregnancy ; refusal of doing research and refusal of spinal anesthesia patients ; patients with coagulopathy ; infection in site of the spinal anesthesia ; any interference with the absorption of oral drugs that can cause digestive disorders ; The disease affects the feeling of pain, such as diabetes, drug addiction ; Monitor the patient is indicative of Abnormal pulse , mean arteria presure ; The need for analgesics for pain relief
     Exclusion criteria during the study:
Abnormal bleeding during surgery ; Intraoperative cardiovascular and brain complications ; Monitor the patient is indicative of abnormal pulse, mean arterial pressure.

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Mean arterial pressure? pulse. Timepoint: Thirty minutes before feeding capsules every ten minutes. Every ten minutes after spinal anesthesia to complete the surgery. Method of measurement: Monitoring of vital signs.;Duration of analgesia in spinal anesthesia. Timepoint: After the onset of anelgesia by spinal anesthesia Until the onset of pain. Method of measurement: Timer(minute).

Secondary Outcome Measures

Name	Time	Method
o exist. Timepoint: No exist. Method of measurement: No exist.