effect of soymilk intake on inflammatory markers and oxidative stress
Phase 2
- Conditions
- Rheumatoid arthritis.Seropositive rheumatoid arthritis
- Registration Number
- IRCT2013030312689N1
- Lead Sponsor
- Vice chancellor for research, Ahvaz Jondishapur University Of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
18-65 years old patient who have Rheumatoid Arthritis according to revised American Rheumatism Association criteria and Rheumatologist diagnosis. The type and dose of drug medication remain constant since 1 month prior and during of the study.
Exclusion criteria: Patients who have chronic disease such as diabetes, cardiovascular, hepatic, kidney, gastrointestinal diseases, and severe infection. Smoking, alcohol consumption, use of dietary supplements and having allergy to soy products or cow’s milk.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method TNF-a. Timepoint: at baseline and end of each intervention. Method of measurement: ELISA.;IL-1. Timepoint: at baseline and end of each intervention. Method of measurement: ELISA.;Hs-CRP. Timepoint: at baseline and end of each intervention. Method of measurement: ELISA.;IL-6. Timepoint: at baseline and end of each intervention. Method of measurement: ELISA.;Adiponectin. Timepoint: at baseline and end of each intervention. Method of measurement: ELISA.;Leptin. Timepoint: at baseline and end of each intervention. Method of measurement: ELISA.;RF. Timepoint: at baseline and end of each intervention. Method of measurement: Nephlometry.;MDA. Timepoint: at baseline and end of each intervention. Method of measurement: Spectrophotometric.
- Secondary Outcome Measures
Name Time Method Blood Pressure. Timepoint: at baseline and end of each intervention. Method of measurement: Blood Pressure Monitor.;Weight. Timepoint: at baseline and end of each intervention. Method of measurement: digital scale.