Natural History of Eosinophilic Esophagitis: A Longitudinal Follow-up Over 10 Years
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- Mayo Clinic
- 入组人数
- 65
- 试验地点
- 1
- 主要终点
- Natural history of treated Eosinophilic Esophagitis (EE)
研究概览
简要总结
Researchers are trying to understand the course of Eosinophilic Esophagitis (EoE), its progression and effects of treatments.
详细描述
Investigators will identify patients from their database who have been diagnosed with Eosinophilic Esophagitis (EE) from the study period 2000 to 2008, based on clinical features and biopsy findings. Participants will be offered a follow up evaluation that includes: evaluation by the Principal Investigator, completion of questionnaires, Esophagram and Esophageal sponge (EsophaCap) cytology.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adults 18 years of age and older
- •Previous participation in the natural history followup study
排除标准
- •Inability to read due to: Blindness, cognitive dysfunction, or English language illiteracy
- •Pregnant women
结局指标
主要结局
Natural history of treated Eosinophilic Esophagitis (EE)
时间窗: approximately 1 year
The number of recurrent symptoms using the modified Mayo Dysphagia Questionnaire (MDQ). The MDQ is a 32 - item instrument in which symptoms are divided into three symptom domains.
Natural history of untreated Eosinophilic Esophagitis (EE)
时间窗: approximately 1 year
The number of recurrent symptoms using the modified Mayo Dysphagia Questionnaire (MDQ). The MDQ is a 32 - item instrument in which symptoms are divided into three symptom domains.
Natural history of treated Eosinophilic Esophagitis (EoE)
时间窗: approximately 1 year
The number of recurrent symptoms using the Eosinophilic Esophagitis Activity Index (EEsAI). The EEsAI provides a visual analogue of foods for subjects to examine and rate for difficulty in swallowing ranging from severe difficulties to No difficulties.
Natural history of untreated Eosinophilic Esophagitis (EoE)
时间窗: approximately 1 year
The number of recurrent symptoms using the Eosinophilic Esophagitis Activity Index (EEsAI). The EEsAI provides a visual analogue of foods for subjects to examine and rate for difficulty in swallowing ranging from severe difficulties to No difficulties.
次要结局
未报告次要终点
研究者
Jeffrey A Alexander
Principal Investigator
Mayo Clinic