Clinical efficacy observation and effect brain region study of acupuncture treatment of depersonalization-derealization disorder by regulating yin and yang

Early Phase 1

• Conditions: 6B66; depersonalization-derealization disorder

• Registration Number: ITMCTR2024000233
• Lead Sponsor: Beijing Anding Hospital, Capital Medical University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

1.Age 18-40 years;
2.Diagnosed by two professionally trained associate chief physicians or above, meeting the DSM-5 criteria for depersonalization-derealization disorder;
3.Stable vital signs, clear consciousness, and a certain level of expressive ability;
4.Cambridge Depersonalization Scale (CDS) score > 70;
5.Able to understand the content of the questions, voluntarily sign the informed consent form, and agree to participate in this study

Exclusion Criteria

1. Individuals with severe suicidal tendencies;
2. Known alcohol or substance dependence;
3. Accompanied by severe or unstable cardiovascular, hepatic, renal, endocrine, or hematologic diseases;
4. Presence of organic brain damage;
5. Obvious abscesses or damage at the acupuncture sites

Study & Design

• Study Type: Interventional study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Cambridge depersonalization scale and CDS-state;

Secondary Outcome Measures

Name	Time	Method
Cognition assessment;Global Assessment of Functioning;fMRI;Hamilton Depression Rating Scale;Hamilton Rating Scale for Anxiety;Zung's Self-rating Depression Scale;Zung's Self-rating Anxiety Scale;