The effect of endurance training and consumption of antioxidant vitamins on disease progression in patients with CVD

Phase 3

Recruiting

Conditions: Coronary artery diseases.
Atherosclerotic heart disease of native coronary artery
I25.1

Registration Number: IRCT20240418061518N1

Lead Sponsor: Islamic Azad University, Rasht Branch

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: All

Target Recruitment: 60

Inclusion Criteria

Subjects have coronary artery disease (with the condition of at least 50% narrowing of at least two main coronary arteries), which has been confirmed by cardiologists based on examinations, complete blood tests, echocardiography, exercise stress test and angiography.

Exclusion Criteria

using of drugs or other antioxidant supplements other than the supplements considered in this research

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Matrix Metalloproteinases 1? 2? 3 and 9. Timepoint: beginning and end of the eight-week experimental period. Method of measurement: Sampling of venous blood.;Tissue inhibitor of Matrix Metalloproteinases 1. Timepoint: beginning and end of the eight-week experimental period. Method of measurement: Sampling of venous blood.

Secondary Outcome Measures

Name	Time	Method
Heart rate of subjects during exercise training. Timepoint: At the beginning, during and at the end of each exercise training session. Method of measurement: Using the cardiac monitoring device with the subjects.;Systolic and diastolic blood pressure of subjects during exercise. Timepoint: At the beginning and at the end of each exercise training session. Method of measurement: Using an analog blood pressure monitor.