Duration (early or late) of antiseizure medication in children.
- Conditions
- Health Condition 1: G049- Encephalitis, myelitis and encephalomyelitis, unspecified
- Registration Number
- CTRI/2021/03/032145
- Lead Sponsor
- All India Institute of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 112
1. Children aged between 1 month-18 years, presented to paediatric emergency/ward/OPD with at least one episode of clinical seizure
2. At least one episode of seizure during the hospital stay
3. Requires at least one dose of intravenous antiepileptic drug
4. Able to receive and tolerate medications via oral or gastric feeding tube route
5. Able to receive and tolerate a diet or enteral feeding (via gastric feeding tube)
1. Clinical suspicion of Non Convulsive Status Epilepticus (Salzburg criteria), but EEG has not ruled out NCSE
2. Refractory nausea, vomiting and/or diarrhea in the last24 hours
3. Use of a feeding tube that terminates distal to the stomach (e.g. jejunal tube)
4. Active gastrointestinal bleeding
5. Any other physical condition, likely to increase risk of aspiration on oral ingestion, impair absorption, first-pass metabolism or bioavailability
6. Caregiver not providing informed consent.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The proportion of children with seizure recurrence within one week from last seizure freedom in both armsTimepoint: One week
- Secondary Outcome Measures
Name Time Method