Older People, Omega-3, and Cognitive Health
Completed
- Conditions
- age-related cognitive decline in older adultsNeurological - Studies of the normal brain and nervous system
- Registration Number
- ACTRN12607000278437
- Lead Sponsor
- Commonwealth Scientific Industrial Research Organisation
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 400
Inclusion Criteria
• fluency in the English language • agree to not commence own n-3 fish-oil (or algal) supplementation throughout the duration of the study
Exclusion Criteria
• already taking n-3 fish-oil (or algal) supplements • inability to swallow capsules• physically unable to attend laboratory/use pen and paper • diagnosed with intellectual disability, clinical depression, dementia • score < 24 on the dementia screeening measure at screening, have had head injury, stroke, coronary artery bypass surgery, any known degenerative neurological disease, history of alcohol or drug abuse
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Rate of cognitive decline[Participants will be assessed on a broad battery of cognitive tasks and measures of wellbeing, at 4 six-monthly intervals.];Change in well being measures[Participants will be assessed on a broad battery of cognitive tasks and measures of wellbeing, at 4 six-monthly intervals.]
- Secondary Outcome Measures
Name Time Method Secondary outcomes are: <br>plasma fatty acid changes<br>blood pressure, oxidative stress and inflammation.[Markers of plasma fatty acid status, oxidative stress, systemic inflammation, and blood pressure will be assessed at each of the 4 six-monthly assessment points.]