Automated Fast Analysis of Neutrophil Phenotypes in Geriatric Hip Fracture Patients

Recruiting

• Conditions: broken hip; hipfracture; 10005942

• Registration Number: NL-OMON51619
• Lead Sponsor: Sint Antonius Ziekenhuis

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 9 April 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 300

Inclusion Criteria

- age 70 years and older
- suspect for subtrochanteric, pertrochanteric of femoral neck fracture
- undergone diagnostic blood sampling as part of the standard-of-care during
acute trauma care

Exclusion Criteria

- polytrauma (ISS >16)
- transferred from other hospitals >24 hours after trauma
- transferred to another hospital after presentation
- immunocompromised status
- active infectious disease

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The main assessed parameters will be the results from the AQUIOS CL® *load &<br /><br>go* flow cytometer, regarding protein expression on the neutrophil surface.<br /><br>These parameters are related to clinical outcome in terms of infectious<br /><br>complications and mortality.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>To assess the impact of surgical intervention on the neutrophil functional<br />phenotype and to distinguish the response to different operative strategies. </p>