Collagenase treatment for ocular burns
Not Applicable
- Conditions
- Health Condition 1: H188- Other specified disorders of cornea
- Registration Number
- CTRI/2021/08/035994
- Lead Sponsor
- Hyderabad Eye Research Foundation
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Patient should be 18 years and above of age.
2.Patient should be able and prepared to complete all required clincial tests and examinations.
3.Patient should be diagnosed with an acute ( <14 days after injury) severe (grade II-IV) unilateral chemical burn.
4.Patient should not have any other ocular abnormality in the injured eye.
5.Able to provide informed consent prior to any study related procedures.
Exclusion Criteria
1. Unwillingness to participate in the study.
2. Inability to come for all follow-up visits.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Proportion of cases showing complete restoration (epithelialization) of the ocular surface on clinical slit-lamp evaluation using fluorescein staining.Timepoint: 28 days
- Secondary Outcome Measures
Name Time Method The proportion of patients showing 2-line improvement in BCVA from baseline will be computed along with 95% CIs.Timepoint: The secondary end points will be at 3-months, 6-months and 1-year follow up visit.