The influence of percutaneous collagen induction with medical needling on patients with burn scars - a prospective interventional study
Not Applicable
- Conditions
- T20-T25T29-T32Burns and corrosions of external body surface, specified by siteBurns and corrosions of multiple and unspecified body regions
- Registration Number
- DRKS00012394
- Lead Sponsor
- BG Klinikum Duisburg gGmbHKlinik für Hand- & Plastische Chirurgie, Brandverletzungen
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 10
Inclusion Criteria
Age: 18 – 70 years
-Healed burn scars at least two years
-Caucasus skin type
-signed declaration of consent
-cooperative patient
-Possibility of anesthesia
Exclusion Criteria
- already performed operative medical needling
- Wound healing problems
- diabetes mellitus type I and II
- Taking cortisone preparations
- Pregnancy / lactation
- Active malignant diseases
- Severe internal medical conditions
- (cardiomyopathy, COPD, renal insufficiency, uncontrolled infections, heart failure NYHA III / IV)
- malignant disease affecting the burn scar
- radiotherapy of the affected skin area
- Psychiatric disorders
- Known HIV or AIDS
- Dependence of drugs
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Improved quality of burn scar tissue based on the POSAS Observer Scale - The changes are based on all examination points. The primary hypothesis relates to examination time t3 (6 months post-surgery).
- Secondary Outcome Measures
Name Time Method The secondary aim is based on descriptive evaluations. <br><br>- VSS: Vancouver Scar Scale,<br>Elevation of the scar quality<br>- Cutometer: objective detection of the<br>Scar quality<br>- BSHS-B: Burn-Specific-HealthScale Letter<br>- SF (36): Shortform (36) <br>