Sphenopalatine ganglion stimulation with acupuncture for perennial allergic rhinitis

Not Applicable

Completed

• Conditions: Moderate-severe perennial allergic rhinitis; Respiratory; Other allergic rhinitis

• Registration Number: ISRCTN21980724
• Lead Sponsor: Chinese Academy of Chinese Medical Sciences (China)

Brief Summary

2015 protocol in http://www.ncbi.nlm.nih.gov/pubmed/25899566 2020 results in https://pubmed.ncbi.nlm.nih.gov/32148537/ (added 01/09/2020)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2014-03-27
• Study Completion: 2015-06-30
• Last Update Posted: 14 September 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 96

Inclusion Criteria

1. Diagnosis of moderate-severe or severe PER, according to the criteria of allergic rhinitis and its impact on asthma (ARIA) initiative
2. Have had PER for greater than 4 days/week, and greater than 4 consecutive weeks, and disease course is more than 1 year
3. Age range is from 18 to 60 years, either sex
4. Completed AR baseline questionnaire and provided written informed consent
5. The physical sign score is greater than or equal to 1 and the symptom score is greater than or equal to 4

Exclusion Criteria

1. Acute sinusitis, active asthma, or diagnosed or suspicious pneumonia
2. Nasal abnormalities or rhinopolypus (polypoid lesion can be included)
3. Had applied antihistamines, anticholinergics, corticosteroids, decongestants or antibiotics within 2 weeks before enrollment
4. Received systemically administered corticosteroids within 6 months before enrolment or special immune therapy within 1 year
5. Received alternative and complementary modality, i.e. acupuncture or herbal medication for treating AR within 2 months
6. Pregnant woman or someone is planning for pregnancy
7. Suffering serious medical conditions such as uncontrolled hypertension, diabetes mellitus requiring insulin injection, past or current malignant tumour, severe dyslipidaemia or liver and kidney dysfunction, anaemia, active pulmonary tuberculosis, other infectious disease or systemic diseases insufficient for acupuncture treatment
8. Heavy smoker

Study & Design

• Study Type: Interventional
• Study Design: Not specified