ChiCTR1900021671已完成Unknown
Transesophageal echocardiography to measure diastolic function in patients undergoing noncardiac surgery under general anesthesia with sevoflurane, with or without nerve block
scientific research fund of department1 个研究点 分布在 1 个国家目标入组 38 人开始时间: 2018年3月1日最近更新:
干预措施
试验速览
- 阶段
- Unknown
- 状态
- 已完成
- 发起方
- 入组人数
- 38
- 试验地点
- 1
- 主要终点
- peak of early diastolic (E) transmitral inflow velocities
研究概览
简要总结
This transesophageal echocardiography study was undertaken to assess left ventricular diastolic function during anesthesia maintenance by sevoflurane alone and sevoflurane + nerve block in elderly patients with diastolic dysfunction.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 61 至 84（—）
- 性别
- All
入选标准
- •This retrospective clinical observational study included 38 patients scheduled for transabdominal operation with American Society of Anesthesiologists physical status I–II, age>60 years, who demonstrated a sinus rhythm and mitral valvular e velocity <10 cm/s and averaged (left ventricular)LV E/e>9cm/s indicating diastolic dysfunction1 with TEE evaluation after anesthesia induction.
排除标准
- •Patients with the following characteristics were excluded: infection at the puncture site, history of allergy to local anesthetics, preexisting neurological disorders, and/or preexisting coagulatory system disorders (recent bleeding from esophageal varicose veins or hypocoagulability with prothrombin time <20% or platelet count <3000/mL).
研究组 & 干预措施
2
七氟醚+神经阻滞
1
七氟醚
干预措施: 七氟醚
结局指标
主要结局
peak of early diastolic (E) transmitral inflow velocities
peak of late diastolic (A) transmitral inflow velocities
mitral lateral annulus movement in early diastole (e)
mitral lateral annulus movement in late diastole (a)
次要结局
- Heart rate (HR)
- Mean arterial pressure (MAP)
研究者
研究点 (1)
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