Development of Standard References of Maximal Inspiratory Pressure and Maximal Expiratory Pressure in Healthy Adults
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- Measure MVV for healthy Koreans and obtain the reference value.
研究概览
简要总结
(1) Maximum respiratory pressure (MRP)1) Maximum inspiratory pressure (maximum intake pressure) and maximum expiratory pressure (MEP) Digital spirometer (Pony FX, COSMED Inc., Italy) are used to measure the micro-paste in a seated position. MIP is based on the pressure maintained for at least 1 second, inhaling or exhaling with maximum effort in the maximum exhalation state (=residual volume) and the maximum exhalation state (=total lung capacity). The maximum positive pressure value of the MEP and the minimum sound pressure value of the MIP are selected among the three or more attempts. 2) Using the MVV (maximum volitional ventilation) Digital spirometer (Pony FX, COSMED Inc., Italy) machine, repeat breathing deeply and quickly for 12 seconds while wearing a nose plug, and multiply it by 5 to obtain the L/min value. (2) Measure the values of the Pneumatic ventilation. · FVC (forced vital capacity): Total expiratory volume of one of the maximum effort gases · FEV1 (forced expiratory volume 1, effort expiratory volume): Ejected expiratory volume of the first second of the maximum effort expiratory volume (FEV1/FVC): FVC ratio, percentage of FVCs, and extraction of the FVC (excessive flow). PEF): Highest speed of effort opportunity
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 19 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •19 to 65 years old.
- •a patient under general anesthesia
- •Patients in ASA class I to II
- •a patient with no history of thoracic anatomy or surgery
- •Patients with normal chest X-ray findings for preoperative evaluation.
排除标准
- •Patients with no natural history of thoracic abnormalities or surgery
- •Patients with asthma, pneumonia, tuberculosis, pneumothorax, chronic obstructive pulmonary disease and epileptic pulmonary disease
- •Patients who have difficulty communicating with the examiner.
结局指标
主要结局
Measure MVV for healthy Koreans and obtain the reference value.
时间窗: up to 1 year
A. The subject sits on a chair and covers his nose with a nose plug. B. The patient prepares the test with the Pony Fx MIP/MEP spirometer connected filter in his mouth. C. Repeat deep and fast breathing for 12 seconds with the start of the test. D. At this time, the assistant looks at the result graph and guides the patient from the side to make the best effort until the end. E. Multiply the result for 12 seconds by 5 to obtain the L/min value of MVV.
Measure MIP for healthy Koreans and obtain the reference value
时间窗: up to 1 year
A. The subject sits on a chair and covers his nose with a nose plug. B. The patient prepares the test with the Pony Fx MIP/MEP spirometer connected filter in his mouth. C. After inhaling as much as possible, exhale strongly through the filter with maximum force. D. At this time, the assistant guides the patient from the side so that the patient can exhale with maximum force. E. Check the results and select a pressure that is maintained for at least 1 second. F. The minimum sound pressure value is selected by attempting the A\~E process more than three times.
Measure MEP for healthy Koreans and obtain the reference value.
时间窗: up to 1 year
A. The subject sits on a chair and covers his nose with a nose plug. B. The patient prepares the test with the Pony Fx MIP/MEP spirometer connected filter in his mouth. C. Breathe out as much as you can, and then breathe in strongly through the filter with maximum force. D. At this time, the assistant guides the patient from the side to breathe in with maximum force. E. Check the results and select a pressure that is maintained for at least 1 second. F. The maximum positive pressure value is selected by trying the A\~E process more than three times.
次要结局
- Check the predictive equation (forced vital capacity)(up to 1 year)
- Check the predictive equation (PEF)(up to 1 year)
- Check the predictive equation (forced expiratory volume 1)(up to 1 year)
- Check the predictive equation (FEV1/FVC)(up to 1 year)