Evaluating the effect of a home training program on hand function in people with Parkinson’s disease,

Not Applicable

Completed

• Conditions: Parkinson's disease; Neurological - Parkinson's disease; Physical Medicine / Rehabilitation - Physiotherapy; Physical Medicine / Rehabilitation - Occupational therapy

• Registration Number: ACTRN12621000274875
• Lead Sponsor: The University of Melbourne

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2021-03-11
• Study Completion: 2024-06-21
• Last Update Posted: 29 July 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

1.A diagnosis of idiopathic PD confirmed by a neurologist
2.Mild to moderate PD (Hoehn & Yahr Staging Scale score of I-III in the ‘on’ phase of the medication cycle)
3.Limitations in daily hand function
4.A stable levodopa medication regime (no changes to medications in the 4 weeks before commencement of the program
5.Independent community living
6.Adequate computer proficiency to participate in web-based video conferencing
7.Sufficient comprehension of English to complete data collection, understand training instructions and give informed consent.

Exclusion Criteria

1. A Deep Brain Stimulator device in situ
2. Neurological conditions other than Parkinson's disease
3. Major musculoskeletal comorbidities of the arms and/or hands

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Recruitment (composite)<br>Recruitment rate - determined by number of eligible participants screened vs. number of participants enrolled as assessed by an audit of the study database. <br>Recruitment data (the number and reasons for exclusion of potential participants and those who decline) will also be recorded. <br><br><br><br><br>[ Following completion of study recruitment.];Acceptability of the hand training program and mode of delivery (Intervention group only) - assessed using a study-specific questionnaire. [ 4 weeks post-commencement of the intervention.];Adherence to the hand training program (Intervention group only) - <br>1. Training diary - participants receiving the intervention will complete a study-specific training diary <br>2. Physitrack app - data on participant access to the home program. [ 4 weeks post-commencement of the intervention]

Secondary Outcome Measures

Name	Time	Method
Self-reported hand function (Activity questionnaires) - evaluated using two validated measures, the Manual Ability Measure 36 (MAM-36) and Dexterity Questionnaire 24 (DextQ-24).[ Pre-intervention and 4, 12 & 24 weeks post-commencement of the intervention.];Hand dexterity - measured with the Purdue Pegboard Test[ Pre-intervention and 4, 12 & 24 weeks post-commencement of the intervention.];Retention rate (primary outcome) - determined by the number of participants at baseline vs. number of participants retained in the study at 4, 12 and 24 weeks post-commencement of the intervention. Assessed by an audit of the study database. [ 4, 12 and 24 weeks post-commencement of the intervention]