NL-OMON24149已完成不适用
Treatment Strategies in Rheumatoid Arthritis: a randomized clinical trial to test the effectiveness of different treatment strategies in patients with early rheumatoid arthritis.
Dutch College of Health Insurance Companies0 个研究点目标入组 508 人开始时间: 待定最近更新:
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 508
研究概览
简要总结
- Arthritis Rheum. 2005 Nov;52(11):3381-90.
2. Clin Exp Rheumatol. 2006 Nov-Dec;24(6 Suppl 43):S-77-82.
3. Ann Intern Med. 2007 Mar 20;146(6):406-15.
4. Ann Rheum Dis. 2007 Sep;66(9):1227-32. Epub 2007 Apr 3.
5. J Rheumatol Suppl. 2007 Nov;80:25-33.
6. Arthritis Rheum. 2008 Feb;58(2 Suppl):S126-35.
7. Arthritis Rheum. 2008 May;58(5):1293-8.
研究设计
- 研究类型
- Interventional
入排标准
入选标准
- •Patients (18 years or older) with rheumatoid arthritis (ACR 1987 criteria), diagnosis since less than 2 years, previously untreated with DMARDs, with active disease (at least 6/66 swollen and at least 6/68 painfull joints, and either ESR 28 mm or more or VAS general wellbeing (by patient) of 20 mm or more).
排除标准
- •1. Previous therapy with DMARDs except for hydroxychloroquine;
- •2. Pregnancy or wish to become pregnant during the study, or childbearing potential without adequate contraception;
研究者
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