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临床试验/NCT01877460
NCT01877460已完成不适用

The Effects of Isovolumetric Preloads of Sodium Alginate-enriched Chocolate Milk on Glycemia, Subjective Appetite and Food Intake in Healthy Young Men

University of Toronto2 个研究点 分布在 1 个国家目标入组 24 人开始时间: 2012年1月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
24
试验地点
2
主要终点
Satiety Change

研究概览

简要总结

This study compares the effects of isovolumetric (325 ml) preloads of chocolate milk supplemented with sodium alginates at incremental doses on inter-meal glucose levels, appetite scores and food intake in healthy adult men. The findings of this study will illustrate whether the addition of sodium alginate to chocolate milk will improve the glycemic properties of chocolate milk and will potentiate its satiating characteristics. This study will also elucidate whether sodium alginates, incorporated into chocolate milk, will influence glycemia, appetite sensations and food intake in a dose-dependent manner. It is hypothesized that there will be a synergy between milk and sodium alginate beyond either alone. When combined with milk components, sodium alginate is expected to improve glycemia and induce satiety more than does either milk alone or alginate alone.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Prevention
盲法
Single (Participant)

入排标准

年龄范围
20 Years 至 30 Years(Adult)
性别
Male
接受健康志愿者

入选标准

  • non-smoking male subjects,
  • aged 20-30 years with a body mass index between 20 and 24.9 kg/m2, were recruited.

排除标准

  • Breakfast skippers,
  • individuals with lactose-intolerance or
  • who are allergic to milk,
  • individuals with gastrointestinal problems and
  • individuals with diabetes or other metabolic diseases were excluded from the study.

结局指标

主要结局

Satiety Change

时间窗: 0, 10, 20, 30, 45, 60, 75, 90 and 120 min (pre-meal) and 140, 170, 200, 230 and 260 min (post-meal) after consumption of the treatments

Pre-meal changes from 0 min; Post-meal changes from 120 min Satiety scores (mm) were assessed using 100-mm "Motivation to Eat" visual analog scale questionnaires. A composite score of the four appetite questions, including Desire to Eat, Hunger, Fullness and Prospective Food Consumption, in the "Motivation to Eat" visual analog scale was calculated to obtain the average appetite score for statistical analysis.

次要结局

  • Food Intake(120 min)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

G. Harvey Anderson

Professor

University of Toronto

研究点 (2)

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