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Isovolumetric and Isocaloric Preloads of Various Types of Milk on Food Intake, Subjective Appetite and Glycemic Response

Phase 1
Completed
Conditions
Diabetes Prevention
Obesity Prevention
Registration Number
NCT01025557
Lead Sponsor
University of Toronto
Brief Summary

The purpose of this protocol is to study the effects of fluid milk products on satiety, food intake, and glucose metabolism in healthy young men and women. Experiment 1: The specific objective is to investigate isovolumetric amounts of milk (2% M.F.), chocolate milk (1% M.F.), a soy beverage, cow's milk-based infant formula, and water (control) on satiety and food intake and on blood glucose before and after a meal. A fixed volume approach is based on the commercially available serving size. Experiment 2 will examine equicaloric amounts of milk (2% M.F.), chocolate milk (1% M.F.), a soy beverage, cow's milk-based infant formula, a glucose drink and water (control) the treatments in order to investigate macronutrient composition on satiety and food intake and on blood glucose before and after the meal.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
52
Inclusion Criteria
  • Healthy
  • Non-smoking
  • Aged 20-30 years
  • Body mass index between 20 and 24.9 kg/m2
Exclusion Criteria
  • Diabetes
  • Medication
  • Lactose-intolerance or allergies to milk
  • Breakfast skippers and those on an energy restricted diet

Study & Design

Study Type
INTERVENTIONAL
Study Design
CROSSOVER
Primary Outcome Measures
NameTimeMethod
Food intake30 minute
Secondary Outcome Measures
NameTimeMethod
Blood glucose0, 10, 20, 30, 50, 80, 110, 140 and 170 minutes

Trial Locations

Locations (1)

University of Toronto

🇨🇦

Toronto, Ontario, Canada

University of Toronto
🇨🇦Toronto, Ontario, Canada

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