Isovolumetric and Isocaloric Preloads of Various Types of Milk on Food Intake, Subjective Appetite and Glycemic Response

Phase 1

Completed

• Conditions: Diabetes Prevention; Obesity Prevention
• Interventions: Other: Dietary intervention

• Registration Number: NCT01025557
• Lead Sponsor: University of Toronto

Brief Summary

The purpose of this protocol is to study the effects of fluid milk products on satiety, food intake, and glucose metabolism in healthy young men and women. Experiment 1: The specific objective is to investigate isovolumetric amounts of milk (2% M.F.), chocolate milk (1% M.F.), a soy beverage, cow's milk-based infant formula, and water (control) on satiety and food intake and on blood glucose before and after a meal. A fixed volume approach is based on the commercially available serving size. Experiment 2 will examine equicaloric amounts of milk (2% M.F.), chocolate milk (1% M.F.), a soy beverage, cow's milk-based infant formula, a glucose drink and water (control) the treatments in order to investigate macronutrient composition on satiety and food intake and on blood glucose before and after the meal.

Detailed Description

Not available

Study Timeline

• Study Start: 2009-09
• Study First Submitted: 2009-12-02
• Study First Submitted QC: 2009-12-02
• Study First Posted: 2009-12-03
• Primary Completion: 2011-06
• Study Completion: 2012-05
• Status Verified: 2012-06
• Last Update Submitted: 2012-06-13
• Last Update Posted: 2012-06-14

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 52

Inclusion Criteria

• Healthy
• Non-smoking
• Aged 20-30 years
• Body mass index between 20 and 24.9 kg/m2

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Exclusion Criteria

• Diabetes
• Medication
• Lactose-intolerance or allergies to milk
• Breakfast skippers and those on an energy restricted diet

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Chocolate milk	Dietary intervention	-
Soy beverage	Dietary intervention	-
Milk	Dietary intervention	-
Infant formula	Dietary intervention	-
Water	Dietary intervention	-

Primary Outcome Measures

Name	Time	Method
Food intake	30 minute

Secondary Outcome Measures

Name	Time	Method
Blood glucose	0, 10, 20, 30, 50, 80, 110, 140 and 170 minutes

Trial Locations

Locations (1)

University of Toronto; 🇨🇦 Toronto, Ontario, Canada