Study of the effect of plant extract on the oral environment
- Conditions
- Healthy Adults
- Registration Number
- JPRN-UMIN000042779
- Lead Sponsor
- Taiyo Kagaku Co., Ltd.
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 40
Not provided
1.Persons who have chronic illness, receiving medication, have a serious disease history 2.Persons who are allergic to the test food 3.Persons who usually drink 1L or more of green tea a day 4.Persons who regularly use medicines, foods for specified health use, health foods, etc. that may affect the oral microbiota 5.Persons who have participated in other tests within the first month before the start of the test, or those who intend to participate in another exam after consenting to this exam 6.Persons who were judged as inappropriate for subjects by the principal investigator 7.Persons who are breastfeeding, pregnant, planning or hoping to become pregnant during the examination period 8.Persons who have removable dentures 9.Persons who are undergoing treatment for dental caries and periodontal disease 10.Persons who usually smoke
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Oral microbiota (16S metagenomic comprehensive analysis) Number of periodontal disease bacteria (Porphyromonas gingivalis, Tannerella forsythia, Fusobacterium spp., Total number of bacteria)
- Secondary Outcome Measures
Name Time Method Dental plaque Swelling of the gums (gingivitis index) Bad breath Tongue coating Questionnaire (self-bad breath, sticky feeling, refreshing feeling)