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Perifere neuropathie als gevolg van vincristine bij kinderen met leukemie: een vergelijking van twee toedieningsvorme

Conditions
Acute lymphoblastic leukemia<br />Peripheral neuropathy<br />Vincristine<br />Chemotherapy<br />
Registration Number
NL-OMON29651
Lead Sponsor
VU University Medical Center Amsterdam
Brief Summary

/A

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
Not specified
Target Recruitment
80
Inclusion Criteria

diagnosed with pediatric ALL

- treated according to the DCOG ALL-11/ALL-12 protocol (medium and high risk patients)

Exclusion Criteria

- younger than 2 years or older than 18 years at time of diagnosis

- not able to comply with scheduled follow-up meausurements

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Peripheral neuropathy
Secondary Outcome Measures
NameTimeMethod
- Quality of life<br /><br>- Costs<br /><br>- Therapeutic effectiveness <br /><br>- Pharmacokinetics <br /><br>- Genotyping<br />
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