Strain-Encoded Magnetic Resonance Imaging for Evaluation of Left Ventricular Function and Acute Myocardial Infarction
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Acute Myocardial Infarction
- Sponsor
- RWTH Aachen University
- Enrollment
- 48
- Locations
- 1
- Primary Endpoint
- Left ventricular function
- Status
- Completed
- Last Updated
- 17 years ago
Overview
Brief Summary
The aim of the study was therefore to evaluate whether myocardial deformation imaging performed by SENC allows for quantification of regional left ventricular function and is related to transmurality states of infarcted tissue in patients with acute myocardial infarction (AMI).
Detailed Description
CMR was performed in 38 consecutive patients with AMI 3±1 days after successful reperfusion using a clinical 1.5 Tesla MR-scanner. Ten healthy volunteers served as controls. SENC is a technique that directly measures peak circumferential strain from long-axis views and peak longitudinal strain from short axis views. Measurements were obtained for each segment in a modified 17 segment model. Wall motion and infarcted tissue were evaluated semi-quantitatively from SSFP cine sequences and contrast-enhanced-MR-images and were then related to myocardial strain. Comparison of peak circumferential strain assessed by SENC and MR-tagging was performed.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Patients with AMI after successful reperfusion
- •Healthy volunteers in control group
Exclusion Criteria
- •No reperfusion
Outcomes
Primary Outcomes
Left ventricular function
Time Frame: 01.01.2007 until 01.02.2007
Secondary Outcomes
- Transmurality(01.01.2007 until 01.02.2007)