Effect of curcumin on systemic inflammatory response syndrome
Phase 3
Recruiting
- Conditions
- sepsis/at risk of sepsis.Systemic inflammatory response syndrome (SIRS) of non-infectious origin
- Registration Number
- IRCT20110123005670N27
- Lead Sponsor
- Tabriz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
Critically ill patients with APACHE II score of 15-30
Positive SIRS
Age over 18 and under 60
At least 10 days hospitalization in ICU
Patients who received enteral nutrition formula
Exclusion Criteria
Parenteral feeding
Enteral nutrition and gavage formula intolerance
Patients expected to die within the next 24 hours
HIV positive patients
Pregnant and lactating women
ileus
Immune disorder
Diabetes melitus
Short bowel syndrome
Pancreatitis
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Protein C. Timepoint: Day 1, 5 and 10 of intervention. Method of measurement: ELISA Kit.;Partial Thromboplastin time. Timepoint: Day 1, 5 and 10 of intervention. Method of measurement: ELISA kit.;Prediction of death. Timepoint: Day 1, 5 and 10 of intervention. Method of measurement: Simplified Acute Physiology Score questionnaire.;Transforming growth factor ß1. Timepoint: Day 1, 5 and 10 of intervention. Method of measurement: ELISA kit.
- Secondary Outcome Measures
Name Time Method