Efficacy of a Mediterranean diet on reproductive outcomes in couples with infertility seeking in vitro fertilisation treatment (the MEDPREP pilot study)
- Conditions
- InfertilityReproductive Health and Childbirth - Fertility including in vitro fertilisation
- Registration Number
- ACTRN12624000936527
- Lead Sponsor
- Associate Professor Lisa Moran
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot yet recruiting
- Sex
- All
- Target Recruitment
- 40
Females scheduled for in vitro fertilisation (with or without intracytoplasmic sperm injection), with oocyte pickup following the intervention. Participation of the male partner in the dietary intervention will be strongly encouraged, but not mandatory.
- Female age 35 to 43 years. No limit for the age of the male partner.
- Use of partner sperm
- Fresh embryo transfer, or frozen to be transferred within 3 months
- Polycystic ovary syndrome
- Use of donor oocytes
- Medical contraindication to in vitro fertilisation
- Weight change of >3 kg in the 6 months prior to recruitment
- Use of frozen sperm
- More than 3 previous unsuccessful in vitro fertilisation attempts
- Preimplantation genetic testing
- Mediterranean Diet Adherence Score (MEDAS) >10 at baseline
- Not willing to be randomised to the diet
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Day 5 embryo yield[These data will be collected from participants' medical records; they are routinely measured as part of the in vitro fertilisation procedure Time point corresponding to the in vitro fertilisation treatment following the dietary intervention]
- Secondary Outcome Measures
Name Time Method