Risk Prediction of Difficult Tracheal Intubation in OSAHS Patient

• Conditions: Difficult Intubation; Airway Obstruction
• Interventions: Diagnostic Test: difficult tracheal intubation

• Registration Number: NCT04506346
• Lead Sponsor: Beijing Tsinghua Chang Gung Hospital

Brief Summary

This study evaluates the risk factors for difficult tracheal intubation in in obstructive sleep apnea hypopnea syndrome(OSAHS) patients undergoing uvulo-palato-pharyngoplast(UPPP)

Detailed Description

OSAHS patients are high risk group of difficult tracheal intubation. In clinical application, unexpected difficult tracheal intubation is not rare. Difficult airway is a significant problem to these patients and the physicans in terms of mortality and morbidity.

This study collects risk factors as physical examinations（including modified Mallampati grade, neck circumference, lateral clinical craniofacial assessment and body mass index ,BMI）, Stopbang scores, polysommographic parameters (including apnea-hypopnea index, AHI and lowest SpO2, LSpO2), and special radiographic parameters in head and neck region. By using statistics method, predictive model to manage risks would be established.

Study Timeline

• Study Start: 2019-09-30
• Study First Submitted: 2020-02-01
• Status Verified: 2020-08
• Study First Submitted QC: 2020-08-06
• Last Update Submitted: 2020-08-06
• Study First Posted: 2020-08-10
• Last Update Posted: 2020-08-10
• Primary Completion: 2021-08-31
• Study Completion: 2021-12-31

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

• diagnosed as OSAHS.
• receive UPPP under general anesthesia in Beijing Tsinghua Changgung Hospital
• ASA grade I or II

Exclusion Criteria

• ASA grade III or above
• had received UPPP
• had fore-teeth loosed
• obstructive sleep apnea hypopnea were caused by hypothyroidism, acromegaly, or vocal cord paralysis.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
OSAHS	difficult tracheal intubation	patients with OSAHS, undergoing UPPP

Primary Outcome Measures

Name	Time	Method
Difficult Tracheal Intubation	1min After tracheal intubation	Grade Ⅲ or Ⅳ according to Cormach-Lehane Grading of laryngoscopic view

Trial Locations

Locations (1)

YAN SIYI; 🇨🇳 Beijing, Beijing, China