The role of dreams in memory consolidation and reactivations during sleep

Completed

Conditions: Memory
Retention
neuro-psychological

Registration Number: NL-OMON54358

Lead Sponsor: Donders Institute for Brain, Cognition, and Behavior, Radboud University Nijmegen

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: Not specified

Target Recruitment: 92

Inclusion Criteria

• Age between 18 and 35 years
• Willingness and ability to sign informed consent
• Physically and mentally healthy
• High dream recall frequency (at least several times a week)
• High English language proficiency (at least 10 items of the BNT)
• Ability to sleep in the sleep laboratory

Exclusion Criteria

• History of or current sleep disorder (PSQI score > 7, skipping sleep in 6
days before adaptation night)
• Current physical or mental illness (BDI * 20 or BAI > 15)
• Medication that influences the sleep/wake cycle and/or memory consolidation
• Daily drug use
• Extreme coffee drinkers (more than 4 cups/day)
• Skin diseases at intended electrode sites (EMG, EEG)
• Chronotype incompatible with study time window (Regular bedtime after 1 am or
later)
• Inability to sleep during the adaptation night (sleep efficiency < 70%)
• Intake of coffee or alcohol on study day
• Contraindications for MRI
• Pregnancy or nursing

Study & Design

Study Type: Observational non invasive

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The main endpoints are the performance in the picture-word association task, as<br /><br>well as emotional valence and arousal rating of the pictures of the<br /><br>picture-word association task. EEG will also be used for sleep staging.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary aims of the proposed research include EEG correlates of dreaming and<br /><br>dream reports and potential analysis of the sleep EEG (e.g. spindle/slow wave<br /><br>analyses).<br /><br>* Other study parameters (if applicable)<br /><br>Other exploratory analysis are possible using the EEG, stool samples and<br /><br>questionnaire data.</p><br>