NCT01058161已完成不适用
High-Field MRI Characterization of Wrist and Hand Cartilage Abnormalities in Inflammatory and Chronic Rheumatisms
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 34
- 试验地点
- 1
- 主要终点
- can be obtained, one could expect an early detection of joint abnormalities
研究概览
简要总结
The present project aims at evaluating the diagnostic potential of high-field MRI (3 Teslas) for joint disease. At this field, given that isotropic image resolution of 400 microns can be obtained, one could expect an early detection of joint abnormalities. The additional aim of this project will be to develop a quantitative analyse of the corresponding high-resolution images.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •gp Suspects or affected by rheumatoid polyarthritis
- •Morning articular Stiffness of at least 15 minutes.
- •Arthalgias or Arthritises of at least three joints(articulations), among which those of the hand.
- •Possible rheumatoid Presence of a factor(mailman) and\or Antibody anti peptides positive citrullinés.
- •Typical possible radiological Hurts on the standard clichés(pictures) of the reached(affected) joints(articulations).
- •gp Affected by stiffening spondylitis with axial and peripheral infringement :
- •. Lumbago and steepness lumbar vertebra inflammatory.
- •Arthralgias and\or peripheral arthritises
- •Possible presence of an allèle HLA
- •Possible presence of a sacro-illite
- •Absence of the other rheumatic markers
- •gp Affected by connectivity with anti-nuclear antibody positive and / or specific antibodies, suffering of polyarthralgias with or without arthritis
- •gp Healthy control
- •gp Presenting a degenerative osteoarthritis of the wrist traumatic comment, noticed radiologically, which will serve as not inflammatory control.
排除标准
- •Claustrophobia,
- •metallic foreign bodies,
- •pacemakers The pregnant women,
- •parturients or who breast-feed are excluded from the study
结局指标
主要结局
can be obtained, one could expect an early detection of joint abnormalities
时间窗: 24 months
次要结局
- will be to develop a quantitative analyse of the corresponding high-resolution images.(24 months)
研究者
研究点 (1)
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