Title in Norwegian: Sunn og Frisk. En Studie av Helseeffekter av Fiskeinntak i Overvektige Voksne (FINS)
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- University of Bergen
- Enrollment
- 183
- Locations
- 1
- Primary Endpoint
- Changes in metabolic status (glucose, lipids, inflammation)
Study Overview
Brief Summary
It has previously been observed that increased fish intake improves the metabolic health of overweight and obese adults, and animal protein improved metabolic health of obese rats. In this project the investigators will investigate whether increased intake of fish or meat improves metabolic health in overweight/obese adults aged 20-55 years when replacing processed food. The hypothesis is that increased intake of unprocessed fish or meat will improve metabolic health in adults as measured by glucose tolerance, lipid metabolism and inflammatory markers.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Prevention
- Masking
- Single (Outcomes Assessor)
Eligibility Criteria
- Ages
- 20 Years to 55 Years (Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •BMI > 27
- •20-55 years
Exclusion Criteria
- •diagnosed diseases such as diabetes, CVD, intestinal diseases, arthritis
- •prescription medications affecting the metabolism of glucose, lipids or the immune system
- •use of supplements containing long chain n-3 fatty acids
- •high intake of fish
- •food allergy
Arms & Interventions
Salmon Group
Participants will eat 150g salmon for dinner, 3 times per week for 12 weeks
Intervention: Salmon Group (Other)
Cod Group
Participants will eat 150g cod for dinner, 3 times per week for 12 weeks
Intervention: Cod Group (Other)
Meat Group
Participants will eat 150g mixed meat for dinner, 3 times per week for 12 weeks
Intervention: Meat Group (Other)
Outcomes
Primary Outcomes
Changes in metabolic status (glucose, lipids, inflammation)
Time Frame: Baseline and end of intervention (12 weeks)
The effects of fish intake on glucose homeostasis, lipid metabolism and inflammation will be assessed.
Secondary Outcomes
- Changes in plasma concentrations of amino acids and their metabolites(Baseline and end of intervention (12 weeks))
- Changes in plasma concentrations of vitamins(Baseline and end of intervention (12 weeks))
Investigators
Oddrun Anita Gudbrandsen
Researcher
University of Bergen