Evaluation of the effect of microneedling and N-acetylcysteine in the treatment of vitiligo
Phase 3
Recruiting
- Conditions
- Vitiligo.Vitiligo
- Registration Number
- IRCT20200826048531N1
- Lead Sponsor
- Iran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
People with vitiligo have symmetrical constants patches
They are between 15-75 years old
No progressive or new lesions for at least the past year
They have not been treated in the last two months
Exclusion Criteria
Patients who have thyroid disorders
Patients with hypertrophic and keloid scars.
At the site of microneedling have pathological lesions, wounds and infections.
Patients who have allergies to N-acetylcysteine .
Patients who are pregnant or breastfeeding.
Patients who plan to become pregnant within the next six months.
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Tensity of lesions. Timepoint: At the beginning of the study (before the intervention) and 2, 4, 6, 8, 10 and 14 weeks after starting treatment. Method of measurement: use of Vitiligo Extent Tensity Index (VETI) score.;Intensity of repigmentation. Timepoint: At the beginning of the study (before the intervention) and 2, 4, 6, 8, 10 and 14 weeks after starting treatment. Method of measurement: use of Vitiligo Extent Tensity Index (VETI) score.
- Secondary Outcome Measures
Name Time Method Treatment Tolerance. Timepoint: At the beginning of the study (before the intervention) and 2, 4, 6, 8, 10 and 14 weeks after starting treatment. Method of measurement: questionnaire (Scoring to pain from 0 to 10).;Therapeutic satisfaction. Timepoint: At the beginning of the study (before the intervention) and 2, 4, 6, 8, 10 and 14 weeks after starting treatment. Method of measurement: questionnaire (Scoring from 0 to 10).