Assessing the impact of blood pressure targets and surgical approach (laparoscopic or open) on continuous urinary oxygenation in patients undergoing general surgical procedures

Phase 2

Completed

• Conditions: Surgery requiring general anaesthesia; Surgery - Other surgery

• Registration Number: ACTRN12623000726651
• Lead Sponsor: Austin Health

Brief Summary

il available as currently under peer-review

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2023-03-30
• Study Start: 2023-07-05
• Last Update Posted: 10 July 2023

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 43

Inclusion Criteria

Adult patients aged equal to or greater than 18 years of age.
Schedule to have either a laparoscopic or open general surgery
Require placement of a urinary catheter as a part of routine clinical care
Participant provides own consent

Exclusion Criteria

Baseline serum creatinine greater than 200µmol.L-1 or an estimated glomerular filtration rate according to the CKD-EPI method below 30ml.min-1.1.73m-2
Patients with acute kidney injury as defined by the KDIGO consensus criteria,
pregnant women
Pre-anaesthetics mean arterial pressure greater than 100mmHg or lower than 65mmHg

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Mean urinary oxygen level throughout the first 150 minutes after incision. [Urine oxygen values as measured by sterile fibre optic luminescence optode, measuring urinary oxygen levels every 0.6 seconds from induction and throughout the entire duration of of the surgical procedure according to allocated blood pressure target group.]