Casein in milk as a functional ingredient for the prevention of sarcopenia
- Conditions
- Sarcopenia
- Registration Number
- NL-OMON20646
- Lead Sponsor
- Maastricht University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 32
Inclusion Criteria
Males
-Aged between 65-85 years
-Healthy, recreationally active
-BMI < 30 kg/m2
Exclusion Criteria
-Female
-Smoking
-Allergies to milk proteins (whey or casein)
-Arthritic conditions
-Over the counter antacids
-Diabetes mellitus type 1 and type 2
-A history of neuromuscular problems
-Individuals on any medications known to affect protein metabolism (i.e. corticosteroids, non-steroidal anti-inflammatories, or prescription strength acne medications).
-Participation in any regular exercise program
-Chronic use of gastric acid suppressing medication or anti-coagulants
-Unstable weight over the last three months
-Pathologies of the gastrointestinal tract
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method fractional synthetic rate
- Secondary Outcome Measures
Name Time Method •Exogenous phenylalanine rate of appearance and plasma availability of phenylalanine.<br>•Total rate of phenylalanine appearance and disappearance <br>•Endogenous phenylalanine rate of appearance <br>