Feasibility of Saliva and Remote Monitoring of Active Cytomegalovirus (CMV) Infection and Symptoms During Ovarian Cancer Treatment

Recruiting

• Conditions: Cancer-related Cognitive Dysfunction; Cytomegaloviral Infection; Fallopian Tube Carcinoma; Primary Peritoneal Carcinoma; Ovarian Carcinoma

• Registration Number: NCT06870539
• Lead Sponsor: Mayo Clinic

Brief Summary

This study evaluates the feasibility and accuracy of using saliva to remotely monitor cytomegalovirus (CMV) infection in individuals receiving treatment for ovarian cancer.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2025-03-06
• Study First Submitted QC: 2025-03-06
• Study Start: 2025-03-07
• Study First Posted: 2025-03-11
• Status Verified: 2025-04
• Last Update Submitted: 2025-04-23
• Last Update Posted: 2025-04-25
• Primary Completion: 2026-03-03
• Study Completion: 2026-03-03

Recruitment & Eligibility

• Status: RECRUITING
• Sex: Female
• Target Recruitment: 28

Inclusion Criteria

• Age ≥ 18
• Ability to read and write in English
• Diagnosed with ovarian cancer (ovarian, primary peritoneal, fallopian tube)
• Receiving care from providers at Mayo Clinic
• Regardless of diseases status, actively receiving treatment for ovarian cancer (frontline, maintenance, progression, recurrence)

Exclusion Criteria

• Pregnant at the time of study participation
• Inability to provide informed written consent
• History of dementia, stroke, brain tumors or other condition which may impair cognitive functioning

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Using saliva and blood samples to remotely monitor cytomegalovirus (CMV) infection	Baseline	Assessed through collection and comparison of blood and saliva samples collected from individuals receiving treatment for ovarian cancer. Samples may be collected in clinic or at home following study enrollment. Saliva will be self-collected using Oragene OGR-600 kits. Blood samples will be collected at the time of another scheduled clinic blood draw (Aim 1) or at home through a home phlebotomy service (Aim 2).

Trial Locations

Locations (2)

University of Minnesota/Masonic Cancer Center; 🇺🇸 Minneapolis, Minnesota, United States

Mayo Clinic in Rochester; 🇺🇸 Rochester, Minnesota, United States