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Pentoxifylline for the treatment of mania

Phase 2
Recruiting
Conditions
Bipolar disorder.
Bipolar disorder
Registration Number
IRCT20090117001556N157
Lead Sponsor
Tehran University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
50
Inclusion Criteria

Diagnosis of bipolar disorder based on DSM-V criteria
Age between 55-18 years
The score of 20 (at least) based on Young Mania Rating Scale

Exclusion Criteria

Systemic disease including hypothyroidism or hyperthyroidism
Cardiac conduction disorder
Drug dependence except nicotine and caffeine
Presence of serious suicide risk
IQ less than 70
History of allergy to any of the used drugs
Pregnant and lactating women
The use of drugs that cause symptoms similar to mania like psychostimulants

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
The severity of manic phase symptoms. Timepoint: Weeks: 0 - 2 - 4 - 6. Method of measurement: By Young Mania Rating Scale (YMRS).
Secondary Outcome Measures
NameTimeMethod
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