Kidney fuNction in people receiving Gender Affirming Hormone Therapy

Recruiting

• Conditions: het betreft fysiologisch onderzoek; kidney function; renal physiologie

• Registration Number: NL-OMON52715
• Lead Sponsor: Vrije Universiteit Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 15 April 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 40

Inclusion Criteria

Transgender individuals starting gender affirming hormone therapy
18 years or older of age

Exclusion Criteria

Iodine allergy
use of prescribed medication

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The main study parameters/endpoints are the measurement of glomerular<br /><br>filtration rate (GFR) and effective renal plasma flow (ERPF) as measured by<br /><br>iohexol and p-amminohippurate (PAH) clearance. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary endpoints are the estimation of intrarenal hemodynamic parameters<br /><br>derived from Gomez equations, markers of tubular injury and changes in systemic<br /><br>hemodynamic properties.</p><br>