Functional Magnetic Resonance Imaging and Reading Deficit in Children With NF1 Children

University Hospital, Toulouse1 site in 1 country25 target enrollmentMarch 2009

ConditionsNeurofibromatosis Type 1

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Neurofibromatosis Type 1
Sponsor: University Hospital, Toulouse
Enrollment: 25
Locations: 1
Primary Endpoint: Percentage of children performing in full the protocol functional MRI
Status: Completed
Last Updated: 10 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

A monocenter pilot study on the acceptability and feasibility of a functional MRI protocol in children with NF1 with or without reading disabilities.

Detailed Description

The principal aim of the study is to highlight the activation of brain area involved phonological and visuo-spatial processing in children with NF1 with or without reading disabilities.

Registry

clinicaltrials.gov

Start Date

March 2009

End Date

April 2015

Last Updated

10 years ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

University Hospital, Toulouse

Responsible Party

Sponsor

Eligibility Criteria

Inclusion Criteria

•Age included between 8 and 12 years
•Child presenting a type 1 neurofibromatosis according to 2 criteria in the following criteria list :
•At least 6 café au lait spots
•2 or more neurofibromas or 1 plexiform neurofibroma
•axillary or inguinal freckling
•1 optic nerf glioma
•2 or more Lisch nodules
•1 osseous lesion as sphenoid dysplasia or thinning of the long bone cortex with or without pseudarthrosis
•1 A first degree relative (parent, sibling, or offspring) with NF1 by the above criteria
•Membership in a national insurance