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The cortical footprint of deep brain stimulation in the superolateralmedial forebrain bundle (slMFB)

Not Applicable
Recruiting
Conditions
F33
Recurrent depressive disorder
Registration Number
DRKS00031120
Lead Sponsor
niversitätsklinikum Freiburg
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
30
Inclusion Criteria

1. Diagnosed with MDD or with OCD
2. Received bilateral slMFB-DBS, that is applied chronically for at least 1 year
3. Able to give written informed consent
4. Compliance to participate in the study
5. Stable drug regimen at least 3 weeks before study entry

Exclusion Criteria

1. Acute psychosis assessed by a psychiatric physician.
2. Patient incapable to follow and perform the task instructions.

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Aim 1: To describe the cortical effects of slMFB-DBS in a chronic stimulation setting,<br>Aim 2: To determine whether these effects (Aim 1.) respond to different DBS stimulation patterns.
Secondary Outcome Measures
NameTimeMethod
Statistically significant differences in oscillatory activity between DBS OFF and DBS ON (high frequency stimulation)
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