on-penetrating deep sclerectomy versus trabeculectomy in primary congenital glaucoma

Not Applicable

• Conditions: Eye Diseases

• Registration Number: PACTR202002874953456
• Lead Sponsor: Faculty of Medicine

Brief Summary

The current study was conducted on 80 eyes. Each of the NPDS and trabeculectomy groups included 40 eyes of 40 patients with the diagnosis of primary congenital glaucoma. The NPDS group mean age was 14.5 + 13.1 months versus mean age of 13.7 + 12.2 months in the trabeculectomy group. Males represented 60 % in the NPDS group and 65% in the trabeculectomy group. There was no statistically significant difference between the two groups regarding the demographic data of the included patients. At the end of the follow up period the mean IOP was 11.2 + 4.5 and 11.1 + 3.4 mmHg with a mean reduction of 16.2 and 17.4 mmHg in NPDS and trabeculectomy groups respectively. There was a statistically significant difference between preoperative and postoperative IOP levels along the whole follow up period for both groups (p < 0.001). At the end of the follow up period i.e. at 36 months postoperative, the complete success rate was 60 % (24 eyes) versus 57.5 % (23 eyes), the qualified success rate was 25 % (10 eyes) versus 25 % (10 eyes), the overall success rate was 85 % (34 eyes) versus 82.5 % (33 eyes), and the rate of failure was 15 % (6 eyes) versus 17.5 % (7 eyes) in NPDS and trabeculectomy groups respectively

Detailed Description

Not available

Study Timeline

• Study Start: 2020-01-11
• Results First Posted: 2020-07-01
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

children presenting with primary congenital glaucoma under the age of 3 years

Exclusion Criteria

Patients were excluded if they had secondary glaucoma i.e. only eyes with PCG were included,
or there was a coexisting ocular pathology e.g. congenital cataract
or a previous ocular surgery.
Patients with incomplete data or follow up period were also excluded.

Study & Design

• Study Type: Interventional
• Study Design: Not specified